CyberKnife robotic radiosurgery system for tumor treatment

The CyberKnife (Accuray, Inc., Sunnyvale, CA, USA) is one of few systems capable of delivering radiosurgery with exquisite accuracy to tumors, cancers and other conditions throughout the body.

CyberKnife radiosurgery for stage I lung cancer: results at 36 months

Image-guided robotic stereotactic radiosurgery of lung tumors with CyberKnife(R) achieves excellent rates of local disease control with limited toxicity to surrounding tissues and, in many cases, might be curative for patients for whom surgery is not an option.

A technique for stereotactic radiosurgery treatment planning with helical tomotherapy.

A robust and efficient planning technique was identified to produce plans of radiosurgical quality using the TomoTherapy treatment planning system. Dose calculation did not exceed a few hours and resulting delivery times were less than 1 hour, which allows the process to fit into a single day radiosurgery workflow. Plan conformity compared favorably with published results for gamma knife radiosurgery. In addition, plan homogeneity was similar to linac-based approaches.

CyberKnife radiosurgery for benign meningiomas: short-term results in 199 patients

The introduction of the CyberKnife extended the indication to 63 patients (>30%) who could not have been treated by single-session radiosurgical techniques. The procedure proved to be safe. Clinical improvement seems to be more frequently observed with the CyberKnife than in our previous linear accelerator experience.

CyberKnife radiosurgery for benign intradural extramedullary spinal tumors

Although more patients studied over an even longer follow-up period are needed to determine the long-term efficacy of spinal radiosurgery for benign extra-axial neoplasms, short-term clinical benefits were observed in this prospective analysis. The present study demonstrates that CyberKnife radiosurgical ablation of such tumors is technically feasible and associated with low morbidity.

Synchronous Bilateral Stage 1A Non-Small Cell Carcinoma

Patient was unwilling to undergo a second thoracotomy, and instead chose to receive CyberKnife® treatment of the lesion with concurrent chemotherapy.

C5 Malignant Peripheral Nerve Sheath Tumor

There were no further treatment possibilities as surgery, conventional radiation therapy and chemotherapy were already attempted without preventing tumor growth.

T6 Spinal Solitary Breast Metastasis

The treatment of both malignant as well as benign tumors of the spine using CyberKnife radiosurgery began in 1997. Treatment of spine lesions using single fraction radiosurgery has been a successful treatment strategy at UPMC over the past four years.

Recurrent Nasopharyngeal Squamous Cell Carcinoma

Radiosurgery is a practical alternative for both boost therapy after external beam radiotherapy and salvage therapy in patients with recurrent NPC.

Ocular Lymphoma

CyberKnife radiosurgery was recommended to provide rapid regression and to maximize the opportunity for local control within the right orbit while minimizing any damage to the optic nerve and other critical structures.